Scientific News

Intestinal microbes could protect against gut inflammation and colorectal cancer

The alterations in gut microbiota composition observed in mice lacking TAK1 can generate a protective immunity against colitis and colorectal cancer.

Gut microbes produce metabolites that mimic human signaling molecules

Fatty acid amides produced by Clostridia can help the bacteria to modulate their host by mimicking human signaling molecules.

Ancient feces reveal dramatic changes in the human microbiota over the past 2,000 years

The evolutionary history of the human microbiota could help to understand the role of present-day gut microbes in health and disease.

COVID-19 could have long-lasting impacts on gut microbiota composition

Targeted manipulation to promote the microbial diversity could be an important strategy to treat long COVID-19 and speed up recovery.

Children gut microbiota mature at different speeds in the first five years of life

Several bacteria associated with human health are acquired late in childhood — albeit with different developmental dynamics.

Bacterial, viral, and fungal interactions influence inflammation and exacerbation in bronchiectasis

The Integrative Microbiomics tool could potentially delineate subtypes of bronchiectasis and other heterogeneous respiratory diseases.

Gut bacteria swap genes at much higher rates in industrialized societies

Gut bacteria from people in industrialized countries exchange genes at much higher rates than bacteria from people living in non-industrialized societies.

How changes in microbiota composition could influence human health

The microbial communities inhabiting the gut have been shown to change in ways that influence the development of disease through blood metabolites.

Breast milk molecule may help support certain gut bacteria, reduce obesity risk in newborns

A molecule in breast milk, called betaine, may lower the risk of obesity by preventing accelerated growth in newborns and supporting bacterial species.

Patients with dry eye disease have a distinct ocular microbiome that may trigger and perpetuate inflammation

Th17 cells and Treg cells, the resident ocular microbiota could potentially trigger and perpetuate inflammation in dry eye disease.

Antibiotic resistance is often spread in the gut microbiota of hospitalized people

A targeted decontamination could be a strategy to control the spreading of carbapenem-resistance plasmids both amoung patients and within patients.

How a mouth-dwelling microbe inhibits the growth of other bacteria

S. mutans produces tryglysin to inhibit the growth of competing species, including other streptococci that could cause opportunistic infection.

Resident bacteria might contribute to opportunistic infections of the respiratory tract

The manipulation of microbiota could improve the outcomes of infections in the respiratory tract cause by opportunistic pathogens.

Gut microbes could help to treat neurological disorders, study in mice suggests

Gut microbes contribute to symptoms associated with neurological conditions. New microbe-inspired therapies could be develop to treat such conditions.

Microbial metabolites could improve efficacy of anticancer drugs

Some gut microbial metabolites boost the efficacy of antitumor drugs by regulating the body’s immune response and could be used as a part of cancer therapy.

George Paraskevakos – Probiotics Prebiotics & New Foods 2021

Executive Director George Paraskevakos presents the role of the International Probiotics Association (IPA) at this year’s Probiotics, Prebiotics & New Foods conference, to be held in September in Rome.

Microbial transplants shape the gut microbiota in people with HIV, pilot trial suggests

Microbial transplants could be used as a non-invasive and safe strategy to manipulate the gut microbiota, which has been linked to HIV infection.

How a foodborne fungus impairs gut healing in Crohn’s disease

Common gut fungi called Debaryomyces hansenii can influence the severity of Crohn’s disease and other inflammatory bowel diseases.

Microbial interactions shape the microbiota of preterm babies

Microbial and fungal communities interactions shape the gut microbiota in preterm babies. The findings could help to develop microbiota interventions.

How the microbiota contributes to symptoms of Parkinson’s disease

The alterations in gut microbial composition could play a role in the gastrointestinal complications associated with Parkinson’s disease.

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