Neuroscience

Gut bacteria and their metabolites may offer new way to diagnose depression

The team developed a machine-learning model using 34 metabolites that could reliably identify depressed individuals.

Microbiota and memory: in ageing mice, Parabacteroides goldsteinii weakens the gut–brain axis

Mechanisms involve medium-chain fatty acids, inflammatory activation of macrophages, reduced vagal signalling, and lower hippocampal activation.

Owning a dog may boost teens’ social skills and mental health through the microbiota

Some bacteria common in dog owners, particularly Streptococcus strains, were linked to fewer behavioral and attention problems.

Review finds no strong evidence for a causal link between gut microbes and autism

Future studies should have clearly defined hypotheses, adequate sample size, standardized protocols, and replication using multiple independent approaches.

Gut-brain connection may be a predictor of Alzheimer’s and Parkinson’s risk

Combining data about gut-brain–related disorders with genetic and other information provides a powerful approach for predicting Alzheimer’s and Parkinson’s disease.

Synbiotics and autism: a novel microbiome-based strategy to improve gut and behavioral health in children with autism spectrum disorder 

A study demonstrates that synbiotic supplementation, alone or combined with GDH, is a safe and effective adjunct therapy for autistic children with DGBI.

Unravelling the secrets of protein glycosylation

DQGlyco identified multiple unique N-glycopeptides, quantified glycopeptide changes, and explored the link between gut microbiome and brain protein functions.

Gut microbes may shape overlooked molecules linked to immunity and brain function

N-acyl lipids are important, overlooked molecules shaped by diet and gut microbes.

The gut-brain axis and the role of the intestinal barrier

The science behind gut-brain communication and the role of intestinal integrity.

Study uncovers new links between gut microbes and multiple sclerosis

Modifying the microbiota could influence multiple sclerosis progression and provide new therapeutic targets.

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