Scientific News
Lactobacillus salivarius can make cancer immunotherapy less effective by producing indole-3-lactic acid (ILA), that weakens the body’s anti-tumor immune response.
Early interventions targeting the infant gut microbiota, especially in babies born by C-section, may reduce the probability of neurodevelopmental conditions such as autism.
Supplementation with key beneficial bacteria, alongside efforts to reduce breastfeeding barriers, may offer scalable strategies to reduce socioeconomic health disparities.
David Suissa, CEO of BYOME LABS, discusses the growing interest in microbiome research, from the gut and vaginal ecosystems to the less explored skin, scalp and oral microbiomes.
The presence of certain microbes was associated with major shifts in tumor gene activity and the immune environment around the cancer.
Julie Rodriguez, researcher at Inserm (National Institute of Health and Medical Research, France) explored the main categories of microbiome-based biomarkers and their potential applications in clinical practice.
Targeting the gut microbiota-ergothioneine pathway may offer a new way to prevent or treat cognitive side effects of antipsychotic drugs.
Supplementing creatine alongside specific gut bacteria such as Bifidobacterium could offer a treatment for depression by restoring brain energy metabolism.
Marta Ciechonska of Salient Bioscience presented the company’s approach to developing standardized, reproducible microbiome tests based on shotgun metagenomic sequencing.
Reducing dietary fat or controlling gut inflammation could help preserve immune cells and protect gut immunity, offering a strategy to prevent diet-related gut diseases.
Maintaining a healthy gut barrier and microbiota, through diet or other interventions, could help prevent bacteria from reaching the brain, helping maintain neurological health.
Gut microbiota, immunity and diet: twenty years of research and the future of personalized nutrition
Francisco Guarner, from Centro Médico Teknon in Barcelona (Spain), discussed the most recent researches in the field of microbiome and nutrition.
Boosting the gut metabolite indoleacrylic acid (IA), either directly or through the probiotic Bifidobacterium longum subsp. infantis, help protect the gut and prevent NEC.
Using probiotics such as LACTIN-V after antibiotic treatment could help prevent bacterial vaginosis, opening the way for tailored treatments based on individual microbiota profiles.
The findings suggest that targeting specific gut microbes or their metabolites could boost fat-burning and metabolism in response to specific diets.
Targeting gut bacteria, their metabolites, or gut-to-brain signaling could offer new strategies to prevent or treat age-related memory decline.
To better define the role of biotics in infant formula, future studies should be specifically designed to assess infection prevention, with adequate sample sizes, harmonised formulations and long-term follow-up.
The question for the next decade is whether healthcare institutions can reorganise around a biology they did not anticipate—one that is relational, systemic, and indifferent to the departmental boundaries medicine…
B. luti plays a crucial role in maintaining gut homeostasis, microbial electron transfer and gut health by producing beneficial metabolites and regulating formate and hydrogen levels.
Modulating the gut microbiota could be a new strategy to harness immune cells for treating colorectal cancer.
