Scientific News

Head impacts in football may be linked to gut microbiota changes

Repeated head impacts, even if minor, can have biological effects.

When food triggers pain: the role of mast cells in IBS

Guy Boeckxstaens of KU Leuven explains how mast cells may alter pain signalling through IgE dependent responses to food antigens and activation of the MRGPRX2 receptor. 

Medical visits may rapidly reshape the microbiota of remote communities

The results may inform programs to preserve microbial diversity while delivering essential care.

Gut bacteria metabolite may help breast cancer to grow

Targeting deoxycholic acid (DCA)-producing gut bacteria could be a way to slow breast cancer progression.

Proteases and mucus degradation in Irritable Bowel Syndrome: emerging mechanisms and research priorities

Nathalie Vergnolle (Inserm, France) discussed the potential role of proteases in altering the intestinal mucus layer in irritable bowel syndrome (IBS).

Gut worms in mother mice linked to stronger antiviral defenses in pups

Microbiota-derived molecules such as IPA may offer a way to strengthen early-life immunity against respiratory viruses.

Autoimmune syndrome may be tied to changes in gut bacteria, fungi, and viruses

Monitoring the gut microbiota could in the future help understand, diagnose, or manage Sjögren syndrome.

Peppermint oil in IBS and functional dyspepsia: choosing treatment beyond efficacy

William Fusco, gastroenterologist at Gemelli University Hospital in Rome, discusses the role of peppermint oil in the management of disorders of gut–brain interaction.

Microbes fine-tune their protein production to make communities more efficient

Microbial communities may be engineered at the protein-expression level because bacteria adjust their protein production in response to specific neighbors.

Specific gut microbe makes sepsis deadlier in mice

Sangeribacter muris KT1-3 made sepsis deadlier by amplifying inflammation driven by TLR4.

A microbiota-based strategy to prevent chemotherapy-induced gastrointestinal toxicity

Maria Rescigno presents a preclinical study investigating a non-absorbable antibiotic with eubiotic properties in a mouse model of gastrointestinal toxicity induced by the chemotherapeutic agent 5-fluorouracil (5-FU).

Health has a source. You were never told

If the soil microbiome is the first link in a chain that terminates in human health, then agricultural policy is health policy.

AI-based donor-matching tool may boost fecal transplant success rates

MOZAIC, an AI model designed to compare donor and recipients microbiotas, predicted the microbiota convergence after FMT with an accuracy of about 80%.

Bacterial metabolite may link irritable bowel syndrome to mood disorders

The findings highlight TnAse producing gut microbiota, indole, and AhR as promising therapeutic targets for IBS-associated affective disturbances.

Outer membrane vesicles: a new player in the microbiota–gut–brain axis

According to Stephen Michael Collins, McMaster University, these vesicles may represent not only a new component of the microbiota–gut–brain axis, but also a promising platform for future targeted drug, vaccine…

Vaginal microbiota compound linked to better development after C-section in mice

Restoring missing maternal microbes after C-section birth could be a new strategy to support early neurodevelopment.

Harnessing the plant microbiome to improve crop resilience and seed performance

The work of Angela Sessitsch, Head of Center at Austrian Institute of Technology, shows that environmental pressures such as drought can substantially reshape the plant microbiome.

Mouth bacteria may migrate to the gut and help drive gastric cancer

Microbes migrating from the mouth to the gut may play a role in gastric cancer and could become targets for diagnosis or treatment.

Gut bacterium may weaken treatment responses in esophageal cancer

Lactobacillus salivarius can make cancer immunotherapy less effective by producing indole-3-lactic acid (ILA), that weakens the body’s anti-tumor immune response.

C-section birth may shape babies’ genes, gut microbiota, and brain development

Early interventions targeting the infant gut microbiota, especially in babies born by C-section, may reduce the probability of neurodevelopmental conditions such as autism.

Subscribe to MicrobiomePost newsletter

Take full advantage of MicrobiomePost‘s features.