Scientific News

Uric acid may drive obesity by altering gut bacteria

Reducing TIP60 in the liver of obese mice reduced intestinal fat absorption. It also lowered uric acid, increased the levels of L. johnsonii, improved blood sugar levels, and reduced liver…

Where the Mediterranean diet begins: five days through Campania’s food country

Travelling with researchers through southern Italy, Percorsi nel Gusto 2026 connected the science of the gut microbiome with the farms, food traditions and communities behind a dietary pattern too often…

IBS, sex differences and the microbiome: exploring the estrogen connection

UCLA’s Lisa Chang explores differences in bowel habits, intestinal transit and pain, discussing how these factors relate to microbial composition and function. 

Gut bacteria’s fatty acids may help keep Candida in check

Microbiota-targeted approaches that boost specific SCFAs could help prevent harmful Candida overgrowth in vulnerable people.

Microbe-sensing immune receptor may help protect against lung fibrosis

Targeting TLR5 could offer a new way to treat or prevent IPF by correcting harmful lung microbiota changes after injury.

Mapping bloating: what symptom location may reveal about IBS and functional dyspepsia

Lukas Michaja Balsiger, KU Leuven, discusses findings linking upper abdominal bloating more closely to functional dyspepsia and lower abdominal bloating to irritable bowel syndrome (IBS). 

Tumor microbiotas may be less common than previously thought

Tumor microbiotas appear mainly in cancers of the mouth and digestive tract. 

Gut microbes may predict diabetes risk years before diagnosis

Diabetes prevention needs to account for diet-microbiota interactions, because some gut microbes appear to predict diabetes risk differently depending on fiber intake.

Auto-brewery syndrome: when the gut microbiota produces alcohol without drinking

William Fusco, Policlinico Gemelli, discusses the gut fermentation syndrome, a rare condition arising when ethanol-producing bacteria or fungi in the gut generate excessive amounts of alcohol from dietary carbohydrates.

Precancerous growths may trigger long-lasting changes on the gut microbiota

Monitoring or reshaping the gut microbiota after adenoma removal could become part of future strategies to reduce colorectal cancer risk.

Head impacts in football may be linked to gut microbiota changes

Repeated head impacts, even if minor, can have biological effects.

When food triggers pain: the role of mast cells in IBS

Guy Boeckxstaens of KU Leuven explains how mast cells may alter pain signalling through IgE dependent responses to food antigens and activation of the MRGPRX2 receptor. 

Medical visits may rapidly reshape the microbiota of remote communities

The results may inform programs to preserve microbial diversity while delivering essential care.

Gut bacteria metabolite may help breast cancer to grow

Targeting deoxycholic acid (DCA)-producing gut bacteria could be a way to slow breast cancer progression.

Proteases and mucus degradation in Irritable Bowel Syndrome: emerging mechanisms and research priorities

Nathalie Vergnolle (Inserm, France) discussed the potential role of proteases in altering the intestinal mucus layer in irritable bowel syndrome (IBS).

Gut worms in mother mice linked to stronger antiviral defenses in pups

Microbiota-derived molecules such as IPA may offer a way to strengthen early-life immunity against respiratory viruses.

Autoimmune syndrome may be tied to changes in gut bacteria, fungi, and viruses

Monitoring the gut microbiota could in the future help understand, diagnose, or manage Sjögren syndrome.

Peppermint oil in IBS and functional dyspepsia: choosing treatment beyond efficacy

William Fusco, gastroenterologist at Gemelli University Hospital in Rome, discusses the role of peppermint oil in the management of disorders of gut–brain interaction.

Microbes fine-tune their protein production to make communities more efficient

Microbial communities may be engineered at the protein-expression level because bacteria adjust their protein production in response to specific neighbors.

Specific gut microbe makes sepsis deadlier in mice

Sangeribacter muris KT1-3 made sepsis deadlier by amplifying inflammation driven by TLR4.

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