Scientific News

Probiotics in focus: key clinical and translational papers shaping the field

Francisco Guarner Aguilar reviewed some of the most significant probiotic-related papers published in recent years, spanning basic research, clinical trials, and population-based studies.

Finding missing human gut microbes in the Amazon: culturing the Yanomami microbiome for future probiotics

Emma Allen-Vercoe, from University of Guelph (Canada) focuses on the gut microbiome of the Yanomami, whose exceptionally strong cardiometabolic health has attracted growing scientific interest.

Nursery interactions can contribute more to babies’ gut microbiotas than family

Even after long breaks, such as summer vacation, babies continued to share more microbes with former nursery peers than with children from other nurseries.

Microbiome-derived bile acid and islet autoimmunity

A longitudinal study aims to explore the trajectories of MCBAs in relation to islet autoimmunity and type 1 diabetes of children.

From dysbiosis to long-term outcomes: Flavia Indrio wraps up PPPP 2026

Prof. Flavia Indrio reflects on the main take-home messages from the congress, which brought together 32 leading international experts in microbiota research, allergy, nutrition, gut-brain axis and lung disease.

When microbiomes turn risky: a one health view of infective competence

Paul Wilmes, University of Luxembourg, explores the concept of infective competence within a One Health framework.

Stem-like cells in the gut sense commensal bacteria to recruit protective immune cells

E. coli 541-15 helps the colon recruit key immune cells that can develop into macrophages.

Mouth bacteria might play an active role in obesity

Computer models combining oral bacteria, their metabolic functions, and saliva chemicals could better distinguish obese from healthy individuals compared with clinical measurements alone. 

Gut bacteria and their metabolites may offer new way to diagnose depression

The team developed a machine-learning model using 34 metabolites that could reliably identify depressed individuals.

A whole-tomato approach to functional nutrition, inflammation, and microbiome modulation

Piergiorgio Natali (Mediterranean Task force for Cancer Control) discusses the importance of improving functional foods as a strategy to support health, particularly during aging.

Gut microbes from young mice boost gut repair

A youthful gut microbiota can improve the regenerative function of aged intestinal stem cells.

Oral microbiota therapy rebuilds gut bacteria to prevent recurrent C. difficile infection

VOS, an FDA-approved oral microbiota therapy, has been shown to reduce infection risk compared to traditional fecal transplants. 

Gut bacterial genes may control how diet influences tumor growth and immunity

Gut microbes can influence cancer outcomes by regulating nutrient availability and uptake in immune cells.

Beyond sequencing: the role of translational research in functional microbiome profiling

Lorenza Putignani, Pediatric Hospital Bambino Gesù, Italy, discusses translational research in the microbiome field.

Personalized microbiota therapies may be key to treating gut diseases

Effective treatment of IBD requires an approach combining tailored donors, microbiota analysis, and diet.

Gut bacteria may be linked to low sperm quality at high altitudes

The findings reveal a gut-testis interplay that may explain why low oxygen environments reduce male fertility at high altitudes.

The gut microbiome: emerging therapeutic perspectives in multiple sclerosis and type 1 diabetes

Marika Falcone of San Raffaele Hospital in Milan discusses the growing evidence linking the gut microbiome to extra-intestinal autoimmune diseases.

The dentist in 2035. Obsolete?

The oral microbiome is not a dental concern. It is a medical frontier.

Specific gut microbes protect mice from deadly bacterial infections after flu

Segmented filamentous bacteria, or SFB, protect mice from these deadly infections by reprogramming specific immune cells in the lungs.

Gut microbiota can predict who benefits from fiber to prevent diabetes

The effectiveness of dietary fiber in improving blood sugar in prediabetes depends on an individual’s gut microbiota.

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