Scientific News

Microbial “fingerprints” in the lungs linked to pneumonia treatment outcomes

Pneumonia involves shifts in the entire lung microbial community, which interact with a person’s immune response.

IBD and the microbiome: between biological complexity and emerging therapeutic signals

Maurizio Vecchi, gastroenterologist at Policlinico of Milan (Italy), discussed the current and potential role of the microbiome in inflammatory bowel disease (IBD).

A mother’s gut microbes and breast milk shape the early infant gut microbiota

Supporting maternal gut health and optimizing breast milk composition could help shape healthy infant gut development.

Microbiota and memory: in ageing mice, Parabacteroides goldsteinii weakens the gut–brain axis

Mechanisms involve medium-chain fatty acids, inflammatory activation of macrophages, reduced vagal signalling, and lower hippocampal activation.

Oral Microbiome: a new window on systemic health—and a clinical opportunity for evidence-based probiotics

Gianfranco Grompone, Chief Scientific Officer at BioGaia GA, discusses the new evidences about oral microbiome.

Breast milk helps seed and shape the infant gut microbiota

The findings may inform strategies to improve early-life gut health as well as infant nutrition and disease prevention.

Simple rectal mucus test shows promise for detecting colon cancer 

Researchers identified 36 bacterial species, particularly Hungatella hathewayi and Intestinimonas butyriciproducens, associated with colorectal cancer.

Food as code

When we eat, we are not adding energy to a furnace. We are running a programme. And like any programme, the outcome depends entirely on the operating system that interprets…

Pregnancy: how dysbiosis may affect placentation, maternal immunity, and the risk of neonatal sepsis

Maria Rescigno (Humanitas University, Rozzano, Milan) discusses the role of dysbiosis during pregnancy and the perinatal period, outlining two potential clinical trajectories.

Dietary protein could influence cholera infection, mouse study shows

Dietary protein influences V. cholerae growth, metabolism, virulence, and competition with gut microbes.

Owning a dog may boost teens’ social skills and mental health through the microbiota

Some bacteria common in dog owners, particularly Streptococcus strains, were linked to fewer behavioral and attention problems.

Gut microbiota, intestinal barrier, and sepsis: from dysbiosis to probiotics—what preclinical evidence suggests

Francesco Franceschi from Policlinico Universitario A. Gemelli IRCCS (Roma) focuses on bacterial translocation across a compromised intestinal barrier as a plausible pathway contributing to sepsis.

Antibiotic-producing gut microbes might raise infection risk

Lantibiotic-producing gut bacteria can prolong gut imbalance and increase susceptibility to dangerous infections after antibiotics.

Toxin produced by gut bacteria may drive ulcerative colitis

MTB and aerolysin drive gut inflammation in ulcerative colitis.

Microbiome testing for post-infectious IBS: a pilot “microbe-informed” approach presented in Brussels

William Fusco, gastroenterologist at Policlinico Universitario Agostino Gemelli, highlighted a recently published pilot study on post-infectious irritable bowel syndrome (IBS) framed within microbial precision medicine and biomarker-driven care.

Nutrient competition may predict how gut microbes respond to drugs

Nutrient competition provides a predictive framework to anticipate and potentially mitigate drug side effects on the gut microbiota.

Gut bacteria and leucine may determine who benefits from exercise 

The interaction between gut microbes, the amino acid leucine and sIL-6R determines a person’s responsiveness to exercise.

Pharmabiotics Conference 2026: where microbiome development meets regulation

Camille Bello, Communication and Membership Manager at Pharmabiotics Research Institute, underscores the conference’s regulatory focus and PRI’s role in guiding microbiome innovations through complex approval pathways.

Pharmabiotics Conference 2026: three days in Brussels on microbiome biomarkers, one health, and a shifting regulatory landscape

Celine Druart, Executive Director at Pharmabiotic Research Institute, discusses the 10th Pharmabiotics Conference in Brussels, from microbiome biomarkers and One Health to key regulatory developments shaping live biotherapeutic products.

L. reuteri LMG P-27481: a new candidate to modulate barrier function and inflammation

Veronica Ojetti, gastroenterologist at San Carlo di Nancy Hospital (Italy), presents findings from a single-center pilot study assessing the effects of L. reuteri LMG P-27481 on the gut microbiota and…

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