Scientific News

Key immune molecule helps keep commensal microbes in check

IgA can modulate the exposure and immune response to commensal microbes, and its levels determine the severity of immune dysregulation and clinical symptoms in people with IgA deficiency.

Commercial manufacture of microbial therapeutics at Sacco Systems: from microliters to tons

Christophe Roca, Head of Pilot Department at Sacco System, talks about development and GMP production of Live Biotherapeutics for all applications.

MBK-01, orally administered biologic medicine based in primary or recurrent Clostridiodes difficile infection

Juan Basterra, CEO at Mikrobiomik, talks about the interim results on MBK-01, the first intestinal microbiota-based biological drug in phase 3 for both primary episode and recurrence of Clostridioides dificile.

Nanomedicine improves symptoms of inflammatory bowel disease in mice

The findings of a new study suggest that the new nanomedicine approach can improve the delivery of TNF-α-siRNA in people with IBD.

Accelerated lung function decline in chronic obstructive pulmonary disease (COPD): a role for airway dysbiosis

Airway dysbiosis was associated with a lung function decline in COPD patients and it might contribute to this phenotype through metabolic interaction with host pathophysiological processes.

The importance of the mechanism of action in probiotics development

Nina Vinot (TargEDys International Sales Director) talks about a new promising way to isolate, study and bring to the market innovative probiotics.

Unlocking the potential of probiotics: genetically engineering Saccharomyces boulardii for effective obesity management

Karl Alex Hedin (Technical University of Denmark) talks about the potential role of genetically engineering Saccharomyces boulardii to produce an anti-obesity peptide.

Unveiling the link between gut microbiome and atrial fibrillation: insights from a large population study

A recent study poses the basis for the use of microbiome profile in AF risk prediction.

Probiotic-based hydrogel can treat yeast infection, support a healthy vaginal microbiota

The findings of a recent study suggest that combining Lactobacillus probiotics with nanozymes can help treat Candida vaginitis and help the growth of beneficial vaginal microbes.

Probionibacteria: from traditional cheese to next generation probiotics

Gwenael Jan (STLO - INRAE, France) talks about the growing interest and knowledge of Propionibacteria, a peculiar actinobacteria that has the potential to become a next generation probiotic.

The skin microbiome: challenges and opportunities in developing probiotics

Amine Zorgani (Microbiome Mavericks) talks about the importance of the skin microbiome in maintaining skin health and the need for continued research in this field.

Microbiota transplant after gastric bypass improves metabolism in mice

The findings of a recent study suggest that the gut microbiota contributes to improve metabolic health after gastric bypass surgery.

A cross-sectional study on the link between gut microbiota and inflammation in bipolar depression

Depressed BD patients present significant alterations in the taxonomic compositions of their gut microbiota, and this may be related to inflammatory pathways and depression severity.

Probiotic sanitation as a sustainable tool for IPC and AMR control

Elisabetta Caselli, University of Ferrara (Italy), talks about a new and innovative use of probiotics to modulate the "hospital microbiome” in order to reduce the use of chemical disinfectants.

IPC 2023: probiotic business framework overview

George Paraskevakos, Executive Director at International Probiotics Association, talks about probiotic and live biotherapeutic products market evolution and perspective.

How infections alter the population of a gut microbe

The findings of a recent study suggest that a mild gastrointestinal infection can alter gut commensal populations in ways that boost the commensal’s ability to proliferate during an infection.

A new mechanism in rheumatoid arthritis aggravation: Fusobacterium Nucleatum-mediated release of FadA-containing outer membrane vesicles

The findings of a recent study imply that Fusobacterium nucleatum may play a causal role in worsening RA, offering potential therapeutic targets for effectively alleviating RA symptoms.

IPC 2023 and the postbiotics session: the gathering of the different parties 

The highlights of the Postbiotics Discussion Panel that took place in Bratislava during IPC 2023.

Gut microbiota as a source of Live Biotherapeutics: the F. prausnitzii case history

Philippe Langella, Research Director at the French National Institute of Agricultural Research, discussed the potential of Faecalibacterium Prausnitzii as Live Biotherapeutics for several disease.

Antibiotics alter the gut microbiota, raise risk of blood infections in preterm babies

The findings of a recent study may help to develop diagnostic or therapeutic approaches to reduce bacterial bloodstream infections in newborns.

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