Pediatrics

C-section birth may shape babies’ genes, gut microbiota, and brain development

Early interventions targeting the infant gut microbiota, especially in babies born by C-section, may reduce the probability of neurodevelopmental conditions such as autism.

Breastfeeding may offset health impacts of poorer socioeconomic status in children

Supplementation with key beneficial bacteria, alongside efforts to reduce breastfeeding barriers, may offer scalable strategies to reduce socioeconomic health disparities.

Microbial metabolite shows promise against deadly infant disease

Boosting the gut metabolite indoleacrylic acid (IA), either directly or through the probiotic Bifidobacterium longum subsp. infantis, help protect the gut and prevent NEC.

Biotics in infant formula: promising evidence, but stronger clinical studies are needed

To better define the role of biotics in infant formula, future studies should be specifically designed to assess infection prevention, with adequate sample sizes, harmonised formulations and long-term follow-up.

Gut microbiota maturation may be linked to infection risk in preterm babies

Bacteria such as Enterococcus faecium and Limosilactobacillus reuteri are key in activating an immune receptor that boosts the activity of protective immune cells.

Region-specific infant gut bacteria may pave the way for tailored probiotics

Bifidobacterium longum and B. infantis are distinct species with strains adapted to local diets, highlighting the importance of developing geographically tailored infant probiotics.

Nursery interactions can contribute more to babies’ gut microbiotas than family

Even after long breaks, such as summer vacation, babies continued to share more microbes with former nursery peers than with children from other nurseries.

Microbiome-derived bile acid and islet autoimmunity

A longitudinal study aims to explore the trajectories of MCBAs in relation to islet autoimmunity and type 1 diabetes of children.

From dysbiosis to long-term outcomes: Flavia Indrio wraps up PPPP 2026

Prof. Flavia Indrio reflects on the main take-home messages from the congress, which brought together 32 leading international experts in microbiota research, allergy, nutrition, gut-brain axis and lung disease.

A mother’s gut microbes and breast milk shape the early infant gut microbiota

Supporting maternal gut health and optimizing breast milk composition could help shape healthy infant gut development.

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