Gastroenterology

How gut microbiota and genetic factors may drive inflammatory bowel disease

By revealing that OTUD3 limits microbiota-driven STING activation, the findings of a new study offer insights into the disease mechanisms of ulcerative colitis and may pave the way to new…

Engineered gut bacteria may help deliver therapies

Engineered bacteria can be used in gut therapies, but maintaining control over their colonization and genetic stability remains challenging.

Impact of calcium on Lactobacillaceae growth and biofilm formation

Calcium ions affect the growth of both L. acidophilus ATCC 4356 and L. plantarum ATCC 14917, despite some differences.

Mice study shows how gut bacteria help train immune cells to prevent inflammation

STING activity is important for gut health and that targeting this molecule could offer new treatments for IBD.

Fiber may boost efficacy of fecal microbiota transplants for ulcerative colitis

Fiber can influence how well bacteria from a fecal microbiota transplant successfully settle and grow in a person’s gut.

Mismatch in fecal transplants could disrupt gut balance and metabolism

Region-specific microbial transplants may be safer and more effective than standard fecal microbiota transplants.

‘Trojan horse’ nanoparticles target cancer and bacteria to boost cancer therapy

Nanoparticle-based approaches are a promising strategy for treating colorectal cancer.

A gut fungus may help protect against advanced liver disease

Fungal metabolites such as FF-C1 may offer a new therapeutic approach for treating MAFLD and related conditions.

Tiny differences in gut bacteria may influence health and disease

Even small differences between strains of gut bacteria—often within the same species—can sway how these microbes interact with the human body and influence disease outcomes.

Certain bile acids might help treat inflammatory bowel disease

TCA can help to manage IBD by supporting the gut barrier and influencing microbiota composition.

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