Gastroenterology

Gut bacteria from mothers with IBD may increase disease risk in children

Changes in gut bacteria raise a child’s chances of developing IBD later in life, offering clues to why the conditions sometimes runs in families.

From microbiota to prognosis: the gut–liver axis moves into clinical care

Francesca Ponziani from Gemelli University Hospital (Italy) highlights how the gut microbiota can become a clinical tool for identifying and stratifying patients, clarifying pathogenic mechanisms, and opening up new therapeutic…

Microbiota–immunity cross-talk: two sides of the same coin in colorectal cancer and IBD

Federica Facciotti, from University of Milano Bicocca, focuses on how the gut microbiota interacts with immune activation, shaping both chronic inflammatory intestinal disorders and oncology, particularly colorectal cancer. 

Gut microbes protect the liver by digesting fatty liver-causing sugar, fish study shows

Gut bacteria help protect the liver by breaking down sorbitol, a sugar made from glucose in the gut.

Some gut bacteria may reduce steroid hormone activity

A gut bacterium, Clostridium steroidoreducens, can chemically modify steroid hormones, including those used to treat IBD. 

Specific gut bacteria regulate intestinal motility by producing serotonin

L. mucosae and L. ruminis can produce serotonin in the gut, where it promotes nerve growth and regulates intestinal motility.

Distinct gut microbes and metabolites underlie differences in irritable bowel syndrome 

Researchers have found that certain gut bacteria and their metabolites differ between IBS subtypes.

Microbiota-derived molecule regulates immune cell metabolism and gut inflammation

Controlling cadaverine levels and the gut bacteria that produce it could help regulate immune cell metabolism and inflammation.

Enteric pathogens as active drivers of dysbiosis: lessons from Bacillus cereus and experimental models of the gut microbiota

Emilia Ghelardi, Professor of Microbiology and Molecular Microbiology at the University of Pisa, explains how pathogens can actively disrupt the integrity of the commensal community.

Reinforcing the gut barrier: how probiotics support intestinal integrity and immune health

Arthur Ouwehand, Technical Fellow at IFF Finland, discusses the components and vulnerabilities of the gut barrier and reviews how probiotics and related dietary interventions can support its structure and function.

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