immunotherapy

Boehringer Ingelheim acquires T3 Pharma, boosting immuno-oncology efforts

In a significant move to expand its immuno-oncology portfolio, Boehringer Ingelheim has acquired T3 Pharmaceuticals AG, a Swiss biotech company specializing in bacterial cancer therapy.

How gut microbes boost immune responses to cancer immunotherapy

The findings show that bacterial metabolites can sensitize cancer cells to treatment with immunotherapy by boosting the expression of HLA class I molecules.

How do antibiotics influence the microbiota’s impacts on immunotherapy?

Understanding how antibiotics influence the microbiota’s impacts on immunotherapy may inform strategies to identify cancer patients that are more likely to respond to cancer treatment.

Microbiota transplant may alleviate intestinal side effects of cancer immunotherapy

The findings of a recent study suggest that FMT is an effective strategy to mitigate the intestinal side effects of cancer immunotherapy.

Engineer single strain LBPs for robust tumor microenvironment disruption

Pedro Correa de Sampaio, Chief Executive Officer at Neobe Therapeutics, talks about the challenges to remove immunosuppressive constraints that prevent the infiltration of immune cells in a subset of cancers.

Antibiotics may alter gut microbes in ways that hinder cancer immunotherapy

The findings of a recent study suggest that targeting the interactions between MAdCAM-1 and specific receptors on the surface of immune cells may help to improve immunotherapy outcomes.

Gut microbes sway how people with lymphoma respond to immunotherapy

The findings of a recent study identified microbiota signatures that may allow clinicians to predict the outcomes of CAR-T immunotherapy.

How the sex hormone-gut microbiome axis influences tumor immunotherapy

Numerous evidences demonstrate the involvement of the sex hormone-gut microbiome axis in regulating the antitumor efficacy of ICIs.

Immune cells may shuttle beneficial gut microbes to boost anticancer responses

The findings of a new study shed light on a general mechanism by which gut bacteria may influence anti-cancer immune responses.

The Future of Microbiome Modulation Immuno-Oncology

Fabio Grassi, Founder at MV BioTherapeutics SA, discussed how to understand the mechanisms of action for microbiome contributions to cancer therapeutic response in patients.

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