Scientific News

How some gut microbes improve responses to cancer immunotherapy

The findings of a recent study suggest that L. johnsonii or its metabolite IPA could be used as a microbial-based approach to improve a person’s response to immunotherapy.

Borderlands Science: How a Video Game is Advancing Microbiome Research

The intersection of gaming and science has birthed an innovative approach to scientific research and public engagement.

Leaky gut is linked to accelerated biological aging in people with HIV

The findings of a recent study suggest that specific microbial signatures are associated with accelerated biological aging.

A gut microbial metabolite may promote blood clot formation

The findings of a recent study suggest that 2MBC exacerbates the susceptibility to thrombosis and may explain why people with COVID-19 are at increased thrombotic risk.

Gut bacteria may contribute to devastating eye diseases

The findings of a recent study suggest that inherited eye diseases are caused in part by gut bacteria that travel to the retina.

The microbiotas of men who have sex with men resemble those of non-Westernized people

The findings of a recent study suggest that specific sexual activities are associated with gut microbiota alterations in men who have sex with men.

Mouth bacteria speed up pancreatic cancer growth in mice

Research done in mice shows that the mouth-dwelling bacterium Porphyromonas gingivalis can travel from the mouth to the pancreas, resulting in lesions that lead to cancer.

Gut microbes may contribute to statin-associated high blood sugar levels

The findings show that statin-induced high blood sugar levels are associated with Clostridium bacteria and bile acids. The work also suggests that ursodiol may help reduce the adverse effects of…

The new frontier: polyclonal antibodies in microbiome editing

Satish Chandran, President and Chief Executive Officer at Prodigy Biotech, Inc., details the company's program aimed at treating alcoholic liver disease, spotlighting Enterococcus faecalis as the primary antagonist.

Diet switching quickly impacts the gut microbiota and immune system

Two weeks of dietary intervention are sufficient to influence host immunity, metabolism and gut microbiota composition.

Gut microbes may influence susceptibility to respiratory infections 

The results of a recent study reveal that the severity of respiratory infections depends at least in part on a complex interplay between the gut microbiota and the immune system.

The role of the microbiome in chronic lung disease

Aran Singanayagam, research group leader at Imperial College London (UK), examined how disturbances in the airway microbiome are instrumental in the development of chronic lung diseases.

Gut microbes may help ease gastrointestinal damage associated with aspirin use

The results of a recent study shed light on the effects of aspirin use on the gut microbiota. The findings may also inform therapies for aspirin-mediated gastrointestinal damage.

Breast milk establishes a ‘protective’ gut microbiota, promoting infant health

The findings of a recent study shed light on the role of complement proteins in breast milk and provide a mechanism through which breastfeeding may provide protection from certain bacterial…

Challenges in clinical trial execution for Live Biotherapeutics

An exclusive interview with Daniel Brownell, Senior Director of Research & Development at AOBiome Therapeutics, whose core technology is ammonia oxidizing bacteria, formulated as a topical suspension of bacteria applied…

Gut microbes can adapt to long-term antibiotic use

The findings of a recent study suggest that antimicrobial-resistance mutations in commensal bacteria can make the microbiota surprisingly resilient to antibiotics.

Microbial signature is associated with severity of ulcerative colitis in children

The findings of a recent study suggest that the gut microbiota contributes to alterations in the levels of metabolites associated with ulcerative colitis.

AI implementation for microbiome small molecule discovery & therapeutics

Antonio Gomes, Principal Scientist at Xbiome, talks about employing deep learning techniques to refine the prediction of natural product structures directly from gene sets.

Gut metabolites may help to predict infection risk after liver transplant

The findings suggest that microbial metabolites can help to predict who is at increased risk of infection after liver transplant. The results may also help to inform microbiota-targeted therapies.

How microbial ‘social networks’ shape host health

Socially transmissible microbes may influence human health and play a hidden role in social evolution.

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