Giorgia Guglielmi

How vitamin A and gut microbiota regulate the intestinal immune system

The gut microbiota reduces the production of retinoic acid, a metabolite of vitamin A, to regulate immune activity and prevent pathogens.

Some commensal bacteria support gut epithelial regeneration

Lactic-acid-producing bacteria support the regeneration of the gut lining by promoting the growth and differentiation of intestinal stem cells.

More evidence that fecal transplants are safe and effective against Clostridium difficile infection

Fecal microbiota transplantation can be safely done either with lyophilized or frozen product, found a clinical trial published in the journal PLOS ONE.

New insights into the formation of the human airway microbiota

The lower airway microbiota forms within the first 2 months of life, influenced by the gestational age at birth and, in premature babies, the delivery mode.

New visions into the transmission of the mammalian gut microbiota

Commensal gut microbes are inherited from parents and change little over generations, whereas pathogens tend to be transmitted between non-kin individuals.

A commensal microbe reverses autism spectrum social deficits in mice

Lactobacillus reuteri can improve social behavior in different mouse models of autism spectrum disorder, researchers have found.

Bifidobacterium bifidum promotes immune tolerance in the gut

A group of cell-wall sugar molecules stimulate the production of pTreg cells, which reduce inflammation and prevent autoimmunity.

The metabolic environment of the gut regulates susceptibility to C. difficile infection

A gut dysbiosis leads to an increase in proline, which gives C. difficile a competitive advantage and favors the development of the infection.

Plant-derived RNAs can shape the gut microbiota

Exosome-like nanoparticles derived from plants contain RNAs that regulate gut microbiota composition and impact on the gut barrier function.

Gut microbiota: new perspectives to beat pancreatic cancer

The microbiota of a cancerous pancreas is different and larger than that of a non-cancerous pancreas, according to a study published in Cancer Discovery.

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