Giorgia Guglielmi

Intestinal microbes could protect against gut inflammation and colorectal cancer

The alterations in gut microbiota composition observed in mice lacking TAK1 can generate a protective immunity against colitis and colorectal cancer.

Gut microbes produce metabolites that mimic human signaling molecules

Fatty acid amides produced by Clostridia can help the bacteria to modulate their host by mimicking human signaling molecules.

Ancient feces reveal dramatic changes in the human microbiota over the past 2,000 years

The evolutionary history of the human microbiota could help to understand the role of present-day gut microbes in health and disease.

COVID-19 could have long-lasting impacts on gut microbiota composition

Targeted manipulation to promote the microbial diversity could be an important strategy to treat long COVID-19 and speed up recovery.

Children gut microbiota mature at different speeds in the first five years of life

Several bacteria associated with human health are acquired late in childhood — albeit with different developmental dynamics.

Gut bacteria swap genes at much higher rates in industrialized societies

Gut bacteria from people in industrialized countries exchange genes at much higher rates than bacteria from people living in non-industrialized societies.

How changes in microbiota composition could influence human health

The microbial communities inhabiting the gut have been shown to change in ways that influence the development of disease through blood metabolites.

Breast milk molecule may help support certain gut bacteria, reduce obesity risk in newborns

A molecule in breast milk, called betaine, may lower the risk of obesity by preventing accelerated growth in newborns and supporting bacterial species.

Antibiotic resistance is often spread in the gut microbiota of hospitalized people

A targeted decontamination could be a strategy to control the spreading of carbapenem-resistance plasmids both amoung patients and within patients.

How a mouth-dwelling microbe inhibits the growth of other bacteria

S. mutans produces tryglysin to inhibit the growth of competing species, including other streptococci that could cause opportunistic infection.

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