infections

SER-155’s early success in stem cell transplants: reducing infections and improving outcomes

Chris Ford, Senior Vice President, Translational Biology at Seres Therapeutics, discusses the development of SER-155, a cultivated bacterial consortium designed to address the unmet medical need of preventing bloodstream infections…

The evolution of REBYOTA: milestones in microbiome-based therapeutics

On the second anniversary of its launch, Ferring Pharmaceuticals’ REBYOTA remains a landmark innovation in the prevention of recurrent Clostridioides difficile.

Gut protozoan worsens asthma while boosting defense against infection

The findings of a recent study suggest that while T. musculis can worsen asthma, it might also help the body fight off infections, offering potential for new treatments targeting the…

The skin can produce its own immune response to control the microbiota

The skin can independently generate immune responses to control the microbiota and prevent infections, without relying on other immune centers.

Early-life microbiota might influence the severity of respiratory infections

The findings suggest that the microbial communities inhabiting an infant’s nose and throat can play a role in the severity of RSV infections.

“Super-donor” microbiota may restore gut health after fecal microbiota transplantation

By suggesting that the diversity and variety of microbial species play a big role in whether the transplanted microbes can successfully colonize a recipient’s gut, the findings could pave the…

Microbiota transplant outperforms antibiotics in restoring gut health after C. difficile infection

The findings show that C. difficile infection affects cholesterol metabolism and disrupts the gut microbiota by reducing beneficial bacteria and increasing harmful ones, with fecal microbiota transplant proving more effective…

Age, sex and lifestyle impact the upper airways microbiota

The findings suggest that the development and maturation of the nasal microbiota are influenced by age and sex, while lifestyle factors shape the throat microbiota.

Artificial intelligence reveals a treasure trove of antimicrobial molecules

The findings suggest that artificial intelligence can help uncover new antibiotics, opening the way for new approaches to antibiotic discovery. The work also offers an open-access resource for antibiotic developers.

How do worms and gut microbes interact during early life?

The authors advocate for further research on worm-microbiota interactions, suggesting that new animal models could help inform strategies for improving health during early life.

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