gut microbiota

Autoimmune syndrome may be tied to changes in gut bacteria, fungi, and viruses

Monitoring the gut microbiota could in the future help understand, diagnose, or manage Sjögren syndrome.

Peppermint oil in IBS and functional dyspepsia: choosing treatment beyond efficacy

William Fusco, gastroenterologist at Gemelli University Hospital in Rome, discusses the role of peppermint oil in the management of disorders of gut–brain interaction.

Microbes fine-tune their protein production to make communities more efficient

Microbial communities may be engineered at the protein-expression level because bacteria adjust their protein production in response to specific neighbors.

Specific gut microbe makes sepsis deadlier in mice

Sangeribacter muris KT1-3 made sepsis deadlier by amplifying inflammation driven by TLR4.

A microbiota-based strategy to prevent chemotherapy-induced gastrointestinal toxicity

Maria Rescigno presents a preclinical study investigating a non-absorbable antibiotic with eubiotic properties in a mouse model of gastrointestinal toxicity induced by the chemotherapeutic agent 5-fluorouracil (5-FU).

AI-based donor-matching tool may boost fecal transplant success rates

MOZAIC, an AI model designed to compare donor and recipients microbiotas, predicted the microbiota convergence after FMT with an accuracy of about 80%.

Bacterial metabolite may link irritable bowel syndrome to mood disorders

The findings highlight TnAse producing gut microbiota, indole, and AhR as promising therapeutic targets for IBS-associated affective disturbances.

Outer membrane vesicles: a new player in the microbiota–gut–brain axis

According to Stephen Michael Collins, McMaster University, these vesicles may represent not only a new component of the microbiota–gut–brain axis, but also a promising platform for future targeted drug, vaccine…

Mouth bacteria may migrate to the gut and help drive gastric cancer

Microbes migrating from the mouth to the gut may play a role in gastric cancer and could become targets for diagnosis or treatment.

Gut bacterium may weaken treatment responses in esophageal cancer

Lactobacillus salivarius can make cancer immunotherapy less effective by producing indole-3-lactic acid (ILA), that weakens the body’s anti-tumor immune response.

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