gut microbiota

Bacterial metabolite may link irritable bowel syndrome to mood disorders

The findings highlight TnAse producing gut microbiota, indole, and AhR as promising therapeutic targets for IBS-associated affective disturbances.

Outer membrane vesicles: a new player in the microbiota–gut–brain axis

According to Stephen Michael Collins, McMaster University, these vesicles may represent not only a new component of the microbiota–gut–brain axis, but also a promising platform for future targeted drug, vaccine…

Mouth bacteria may migrate to the gut and help drive gastric cancer

Microbes migrating from the mouth to the gut may play a role in gastric cancer and could become targets for diagnosis or treatment.

Gut bacterium may weaken treatment responses in esophageal cancer

Lactobacillus salivarius can make cancer immunotherapy less effective by producing indole-3-lactic acid (ILA), that weakens the body’s anti-tumor immune response.

C-section birth may shape babies’ genes, gut microbiota, and brain development

Early interventions targeting the infant gut microbiota, especially in babies born by C-section, may reduce the probability of neurodevelopmental conditions such as autism.

Breastfeeding may offset health impacts of poorer socioeconomic status in children

Supplementation with key beneficial bacteria, alongside efforts to reduce breastfeeding barriers, may offer scalable strategies to reduce socioeconomic health disparities.

Microbiome-based biomarkers: challenges on the path from research to clinical practice

Julie Rodriguez, researcher at Inserm (National Institute of Health and Medical Research, France) explored the main categories of microbiome-based biomarkers and their potential applications in clinical practice.

Mouse study links cognitive side effects of antipsychotics to gut microbes

Targeting the gut microbiota-ergothioneine pathway may offer a new way to prevent or treat cognitive side effects of antipsychotic drugs.

Gut microbes help deliver brain energy molecule, offering new path to treat depression

Supplementing creatine alongside specific gut bacteria such as Bifidobacterium could offer a treatment for depression by restoring brain energy metabolism.

From microbiome profiling to ibd diagnostics: Salient Bioscience advances standardized metagenomic testing

Marta Ciechonska of Salient Bioscience presented the company’s approach to developing standardized, reproducible microbiome tests based on shotgun metagenomic sequencing. 

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