gut microbiota

Short-term steroid use may affect metabolism and immunity by reshaping gut bacteria 

Researchers set up a clinical trial to study how glucocorticoids affected the gut microbiota, metabolism, and immunity in healthy young men.

Microbiota–immunity cross-talk: two sides of the same coin in colorectal cancer and IBD

Federica Facciotti, from University of Milano Bicocca, focuses on how the gut microbiota interacts with immune activation, shaping both chronic inflammatory intestinal disorders and oncology, particularly colorectal cancer. 

Gut microbes protect the liver by digesting fatty liver-causing sugar, fish study shows

Gut bacteria help protect the liver by breaking down sorbitol, a sugar made from glucose in the gut.

Largest oral microbiota catalog reveals bacteria linked to oral and systemic health 

The researchers created a microbial catalog, which they called HROM (human reference oral microbiome), containing 72,641 high-quality genomes from 3,426 species.

Microbial metabolites may help immune cells fight melanoma 

Diet and gut microbes can shape immune cell function and improve responses to anti-cancer therapy.

Some gut bacteria may reduce steroid hormone activity

A gut bacterium, Clostridium steroidoreducens, can chemically modify steroid hormones, including those used to treat IBD. 

Specific gut bacteria regulate intestinal motility by producing serotonin

L. mucosae and L. ruminis can produce serotonin in the gut, where it promotes nerve growth and regulates intestinal motility.

Distinct gut microbes and metabolites underlie differences in irritable bowel syndrome 

Researchers have found that certain gut bacteria and their metabolites differ between IBS subtypes.

Fecal profiling of pancreatic cancer

Results of a recent study showed reduced microbial diversity and distinct microbial profile in the two groups of PC patients.

Gut bacteria may help predict lung cancer treatment success

Changes in gut bacteria, especially Akkermansia, could predict treatment success in people with lung cancer.

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