From dysbiosis to long-term outcomes: Flavia Indrio wraps up PPPP 2026

Prof. Flavia Indrio reflects on the main take-home messages from the congress, which brought together 32 leading international experts in microbiota research, allergy, nutrition, gut-brain axis and lung disease.

When microbiomes turn risky: a one health view of infective competence

Paul Wilmes, University of Luxembourg, explores the concept of infective competence within a One Health framework.

Stem-like cells in the gut sense commensal bacteria to recruit protective immune cells

E. coli 541-15 helps the colon recruit key immune cells that can develop into macrophages.

Mouth bacteria might play an active role in obesity

Computer models combining oral bacteria, their metabolic functions, and saliva chemicals could better distinguish obese from healthy individuals compared with clinical measurements alone. 

Gut bacteria and their metabolites may offer new way to diagnose depression

The team developed a machine-learning model using 34 metabolites that could reliably identify depressed individuals.

A whole-tomato approach to functional nutrition, inflammation, and microbiome modulation

Piergiorgio Natali (Mediterranean Task force for Cancer Control) discusses the importance of improving functional foods as a strategy to support health, particularly during aging.

Gut microbes from young mice boost gut repair

A youthful gut microbiota can improve the regenerative function of aged intestinal stem cells.

Oral microbiota therapy rebuilds gut bacteria to prevent recurrent C. difficile infection

VOS, an FDA-approved oral microbiota therapy, has been shown to reduce infection risk compared to traditional fecal transplants. 

Gut bacterial genes may control how diet influences tumor growth and immunity

Gut microbes can influence cancer outcomes by regulating nutrient availability and uptake in immune cells.

Beyond sequencing: the role of translational research in functional microbiome profiling

Lorenza Putignani, Pediatric Hospital Bambino Gesù, Italy, discusses translational research in the microbiome field.

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