Gastroenterology
William Fusco, Policlinico Gemelli, discusses the gut fermentation syndrome, a rare condition arising when ethanol-producing bacteria or fungi in the gut generate excessive amounts of alcohol from dietary carbohydrates.
Monitoring or reshaping the gut microbiota after adenoma removal could become part of future strategies to reduce colorectal cancer risk.
Guy Boeckxstaens of KU Leuven explains how mast cells may alter pain signalling through IgE dependent responses to food antigens and activation of the MRGPRX2 receptor.
Nathalie Vergnolle (Inserm, France) discussed the potential role of proteases in altering the intestinal mucus layer in irritable bowel syndrome (IBS).
William Fusco, gastroenterologist at Gemelli University Hospital in Rome, discusses the role of peppermint oil in the management of disorders of gut–brain interaction.
Microbial communities may be engineered at the protein-expression level because bacteria adjust their protein production in response to specific neighbors.
Maria Rescigno presents a preclinical study investigating a non-absorbable antibiotic with eubiotic properties in a mouse model of gastrointestinal toxicity induced by the chemotherapeutic agent 5-fluorouracil (5-FU).
MOZAIC, an AI model designed to compare donor and recipients microbiotas, predicted the microbiota convergence after FMT with an accuracy of about 80%.
Microbes migrating from the mouth to the gut may play a role in gastric cancer and could become targets for diagnosis or treatment.
The findings suggest that targeting specific gut microbes or their metabolites could boost fat-burning and metabolism in response to specific diets.
