Gastroenterology

Beyond the colon: rethinking the small intestine’s role in IBS

Tim Vanuytsel, Associate Professor and gastroenterologist at UZ Leuven, explores why research should look beyond the colon, particularly given the early onset of symptoms after food intake in many patients.

IBS, sex differences and the microbiome: exploring the estrogen connection

UCLA’s Lisa Chang explores differences in bowel habits, intestinal transit and pain, discussing how these factors relate to microbial composition and function. 

Mapping bloating: what symptom location may reveal about IBS and functional dyspepsia

Lukas Michaja Balsiger, KU Leuven, discusses findings linking upper abdominal bloating more closely to functional dyspepsia and lower abdominal bloating to irritable bowel syndrome (IBS). 

Colon-targeted vitamin B2: how delivery technology could reshape the biotics market

Humiome® B2 uses a patented coating technology intended to transport riboflavin through the upper gastrointestinal tract and release most of it in the ileal-colonic region.

Auto-brewery syndrome: when the gut microbiota produces alcohol without drinking

William Fusco, Policlinico Gemelli, discusses the gut fermentation syndrome, a rare condition arising when ethanol-producing bacteria or fungi in the gut generate excessive amounts of alcohol from dietary carbohydrates.

Precancerous growths may trigger long-lasting changes on the gut microbiota

Monitoring or reshaping the gut microbiota after adenoma removal could become part of future strategies to reduce colorectal cancer risk.

When food triggers pain: the role of mast cells in IBS

Guy Boeckxstaens of KU Leuven explains how mast cells may alter pain signalling through IgE dependent responses to food antigens and activation of the MRGPRX2 receptor. 

Proteases and mucus degradation in Irritable Bowel Syndrome: emerging mechanisms and research priorities

Nathalie Vergnolle (Inserm, France) discussed the potential role of proteases in altering the intestinal mucus layer in irritable bowel syndrome (IBS).

Peppermint oil in IBS and functional dyspepsia: choosing treatment beyond efficacy

William Fusco, gastroenterologist at Gemelli University Hospital in Rome, discusses the role of peppermint oil in the management of disorders of gut–brain interaction.

Microbes fine-tune their protein production to make communities more efficient

Microbial communities may be engineered at the protein-expression level because bacteria adjust their protein production in response to specific neighbors.

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