Oncology

Microbial metabolite could boost efficacy of immunotherapy in pancreatic cancer

A gut microbial metabolite called trimethylamine N-oxide, or TMAO, could improve immunotherapy success in pancreatic cancer.

How Microbiotica Developed MB097, Live Bacterial Therapeutic that Could Boost Cancer Treatments

Ghaith Bakdash described how Microbiotica discovered a specific microbiome signature in patients responder to immune-oncology drugs such as anti-PD1 / PDL1 and developed a new bacterial consortium.

Bacteria in tumors may help cancer to metastasize

New research indicates that the tumor-resident microbiota can promote the formation of metastases as well as the survival of cancer cells during tumor progression.

Microbial metabolite may boost antitumor immunity in aggressive breast cancer

Researchers have found that a specific microbial metabolite may boost the efficacy of anticancer therapy in people with TNBC. The findings could inform the development of improved treatments for TNBC.

Lung microbiota may influence outcome of bone marrow transplant

New research investigates the role of lung microbiota in pediatric patients with lung infection or injury after bone marrow transplantation.

Specific gut bacteria may improve immunotherapy for melanoma

The findings could help to develop microbiota-based strategies to advance immunothery treatments for melanoma.

A probiotic boosts the efficacy of anti-cancer therapy, small trial suggests

Researchers have found that combining a probiotic product with immunotherapy may boost anti-tumor responses in people with advanced kidney cancer.

Akkermansia muciniphila can be a biomarker of response to cancer therapy, study suggests

Akkermansia can be used as a biomarker to identify who is likely to respond to treatment with immune checkpoint inhibitors. A new study published in Nature Medicine claims

A high-fiber diet may improve melanoma patients’ response to immunotherapy

A high-fiber diet may improve melanoma patients’ response to immunotherapy. A new study published in Science claims.

How a gut microbe may suppress colorectal cancer growth

Lactobacillus reuteri can protect against colorectal cancer through reuterin, one of its metabolites. A new study published in Cencer Cell claims

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