Immunology

Gut microbes help keep immune cells anchored in the intestine

Targeting the microbiota could be a new way to strengthen gut immunity and develop treatments for inflammatory bowel diseases such as Crohn’s disease.

Breast milk antibodies train newborn gut immunity, mice study shows

Antibodies in breast milk “teach” a newborn’s gut immune system to respond appropriately to microbes and maintain intestinal balance without causing unnecessary inflammation.

Healthy immune cells may protect the gut barrier, prevent age-related inflammation 

Maintaining healthy T cells is key to preserving gut health and preventing chronic inflammation that drives aging-related diseases.

Microbe-mimicking food contaminants shape immune development in mice 

Dietary LPS can mimic microbial signals and drive gut immune development, with early-life being a critical window for shaping gut immunity.

Microbial metabolites may restore infant immune function after antibiotic exposure

Bacterial metabolites such as inosine could be used as a therapy to strengthen infant immunity after early microbiota disruption.

Gut microbes may shape overlooked molecules linked to immunity and brain function

N-acyl lipids are important, overlooked molecules shaped by diet and gut microbes.

Gut protozoan worsens asthma while boosting defense against infection

The findings of a recent study suggest that while T. musculis can worsen asthma, it might also help the body fight off infections, offering potential for new treatments targeting the…

Artificial intelligence reveals a treasure trove of antimicrobial molecules

The findings suggest that artificial intelligence can help uncover new antibiotics, opening the way for new approaches to antibiotic discovery. The work also offers an open-access resource for antibiotic developers.

New antibiotic kills harmful bacteria while sparing the gut microbiota

The findings of a recent study may inform the development of antibiotics that kill harmful bacteria and not beneficial ones.

Gut microbiota may shape a newborn’s immune system through serotonin production

The findings of a recent study suggest that the infant microbiota produces neurotransmitters that are required for the development of the immune system.

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