Immunology

Gut fungi may be linked to inflammation in severe COVID

The findings of a recent study suggest that mycobiota changes during a SARS-CoV-2 infection could contribute to inflammation associated with severe COVID.

Study reveals the microbiota of people with genetic immune deficiency

A recent study analyzed microbial colonization in people with RAG deficiency to shed light on the effects of secondary immunodeficiencies.

How Akkermansia and Lactobacillus plantarum could revolutionize treatment for Lupus through immune regulation

This study demonstrated fundamental mechanisms through which A. muciniphila and L. plantarum modify the gut microbiota and control immune responses in the SLE mouse model.

Gut microbes may trigger life-threatening reaction to stem cell transplants

The findings of a recent study uncover how gut microbes may contribute to trigger GVHD, suggesting potential targets for therapies.

Key immune molecule helps keep commensal microbes in check

IgA can modulate the exposure and immune response to commensal microbes, and its levels determine the severity of immune dysregulation and clinical symptoms in people with IgA deficiency.

Nosocomial infection risks in critical illness: the microbiota-immune metasystem connection

An altered metasystem linking the gut microbiota and systemic immune response could lead to impaired host defense and increased vulnerability to hospital-acquired infections in cases of severe illness.

How some gut bacteria avoid immune surveillance

The immune system tolerates flagellins of commensal bacteria while mounting an immune response against flagellins produced by pathogens.

COVID-19 may disrupt gut microbiota to increase risk for other infections

Microbiota alterations in COVID-19 patients appeared to be associated with secondary infections of the blood by gut bacteria: four cases of positive blood cultures of Staphylococcus species were identified.

Some gut bacteria may trigger autoimmunity in rheumatoid arthritis

The findings of a recent study suggest that a specific strain of Subdoligranulum can drive the production of autoantibodies in rheumatoid arthritis.

How gut bacteria may evolve to become harmful

The findings of a new research show that gut bacteria can become harmful over time by gaining the ability to escape the intestine and persist in other organs where they…

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