colorectal cancer

Microbiota–immunity cross-talk: two sides of the same coin in colorectal cancer and IBD

Federica Facciotti, from University of Milano Bicocca, focuses on how the gut microbiota interacts with immune activation, shaping both chronic inflammatory intestinal disorders and oncology, particularly colorectal cancer. 

Gut bacteria studied at subspecies level reveal links to colorectal cancer

Profiling the human gut microbiota at the subspecies level, rather than at the species- or strain-level, provides more reproducible insights into how specific bacteria influence health and disease.

‘Trojan horse’ nanoparticles target cancer and bacteria to boost cancer therapy

Nanoparticle-based approaches are a promising strategy for treating colorectal cancer.

Genetic variant linked to colorectal cancer may boost tumor-associated bacteria

Genetic factors can influence tumor-associated microbes, offering insights into colorectal cancer progression and potential therapeutic targets.

Distinct Fusobacterium nucleatum populations linked to colorectal cancer

Each Fusobacterium nucleatum population has unique traits and distribution patterns across body sites and conditions such as colorectal cancer and Crohn’s disease.

How exercise boosts gut health, helping prevent chronic diseases

Understanding the complex interactions between exercise, diet and gut health can help to develop approaches to influence the gut microbiota, boost immunity and prevent or manage gastrointestinal diseases.

Gut microbes protect against colorectal cancer by regulating tumor-promoting gene

The microbiota plays a protective role against colorectal cancer by regulating Snhg9.

Gut microbes may help overcome immunotherapy resistance in gastrointestinal cancer

The findings support the idea that the gut microbiota modulates immune responses, suggesting new avenues for cancer treatment.

Microbial metabolites promote colon cancer by suppressing anti-tumor responses

A recent study demonstrated causation between microbial DCA metabolism and anti-tumor CD8+ T cell response in colorectal cancer.

Researchers associate microbial signatures with two types of precancerous gut lesions

By providing insights into how the gut microbiota influences cancer susceptibility, the findings may help to develop new therapies or dietary interventions.

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