Oncology

Gut microbes may promote the recovery of liver function in cancer patients

The findings of a recent study suggest that modulating the gut microbiota in people with liver cancer can improve their health outcomes after surgery.

Antibiotics alter the gut microbiota in ways that disrupt responses to immunotherapy

The findings of a recent study suggest that antibiotics should be prescribed with caution in cancer patients who are planning to receive PD-1 inhibitors.

Linking gut microbiota diversity to survival outcomes in children’s stem cell transplants

Results from a recent study suggest a correlation between the diversity and composition of the gut microbiota prior to transplantation and both the patient's survival and the probability of developing…

The mouth microbiota may forecast the recurrence of oral cancer

The findings of a recent study suggest that the composition of the mouth microbiota can be used to predict the recurrence of oral cancer.

How gut microbes boost immune responses to cancer immunotherapy

The findings show that bacterial metabolites can sensitize cancer cells to treatment with immunotherapy by boosting the expression of HLA class I molecules.

How do antibiotics influence the microbiota’s impacts on immunotherapy?

Understanding how antibiotics influence the microbiota’s impacts on immunotherapy may inform strategies to identify cancer patients that are more likely to respond to cancer treatment.

Microbiota transplant may alleviate intestinal side effects of cancer immunotherapy

The findings of a recent study suggest that FMT is an effective strategy to mitigate the intestinal side effects of cancer immunotherapy.

Antibiotics may alter gut microbes in ways that hinder cancer immunotherapy

The findings of a recent study suggest that targeting the interactions between MAdCAM-1 and specific receptors on the surface of immune cells may help to improve immunotherapy outcomes.

Preclinical data for MaaT03X, designed to improve response rate to immune checkpoint inhibitors in a solid tumor indication

Nathalie Corvaïa, Chief Scientific Officer at MaaT Pharma, gives an overview of preclinical and clinical results for MaaT013 and MaaT033.

Researchers associate microbial signatures with two types of precancerous gut lesions

By providing insights into how the gut microbiota influences cancer susceptibility, the findings may help to develop new therapies or dietary interventions.

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