Gastroenterology

Nosocomial infection risks in critical illness: the microbiota-immune metasystem connection

An altered metasystem linking the gut microbiota and systemic immune response could lead to impaired host defense and increased vulnerability to hospital-acquired infections in cases of severe illness.

Arresting microbiota development stunts immune system maturation in mice

A recent study shows that microbiota maturation during weaning contributes to normal immune development and protection from infection.

Epsilon toxin-producing Clostridium perfringens colonize the gut of multiple sclerosis patients

ETX-producing C. perfringens strains are biologically plausible pathogens in MS that trigger inflammatory demyelination.

Gut microbes sway how people with lymphoma respond to immunotherapy

The findings of a recent study identified microbiota signatures that may allow clinicians to predict the outcomes of CAR-T immunotherapy.

Gut bacteria Parabacteroides Distasonis: a new hope for the treatment of inflammatory arthritis

The findings of a recent study reveal that P. distasonis and its metabolites could be promising candidates for treating RA.

A mother’s diet can change the infant microbiota, prevent respiratory infection

Diet-induced changes in the gut microbiota confer protection against respiratory infections by regulating the development of key components of the immune system.

How the sex hormone-gut microbiome axis influences tumor immunotherapy

Numerous evidences demonstrate the involvement of the sex hormone-gut microbiome axis in regulating the antitumor efficacy of ICIs.

How a common bacterium colonizes the gut

The findings of a recent study suggest that other gut microbes use liquid-liquid phase separation to colonize the gut, opening the way for new microbiota-based clinical applications.

Some gut microbes are associated with depression in premenopausal women

The findings of a recent study suggest that estradiol-degrading bacteria could be therapeutic targets for treating depression in some women.

Microbial metabolite may damage the DNA of gut stem cells

The findings of a recent study suggest that tilimycin-producing bacteria can cause genetic mutations in the colon and increase a person’s susceptibility to disease.

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