Oncology

Specific gut bacteria reduce ovarian cancer progression in mice

The findings of a recent study tie the gut microbiota to immune surveillance of ovarian cancer and may inform new treatment approaches.

The Future of Microbiome Modulation Immuno-Oncology

Fabio Grassi, Founder at MV BioTherapeutics SA, discussed how to understand the mechanisms of action for microbiome contributions to cancer therapeutic response in patients.

Fever after cancer therapy may be linked to specific gut microbes

The findings of a new research suggest that dietary and antibacterial strategies may help to prevent neutropenia-related fever after cancer therapy.

How the tumor microbiota may reduce the efficacy of cancer drugs

A recent study confirms that 5-FU exerts part of its anti-cancer effects through inhibiting the growth of F. nucleatum, the commensal associated with colorectal cancer progression.

DNA-damaging microbial metabolites found in people with inflammatory bowel disease

The findings of a recent study suggest that DNA damage-inducing microbial metabolites such as indolimines play a role in the development of colorectal cancer.

Tumor-microbiota interactions may help to identify new treatments for pancreatic cancer

The findings of a new research may help to develop improved diagnostic or treatment approaches for pancreatic cancer.

Studies reveal the fungal communities associated with tumors

New studies provide evidence that there may be fungi within tumors and could also help to diagnose certain types of cancer or predicting their course.

Microbial metabolite could boost efficacy of immunotherapy in pancreatic cancer

A gut microbial metabolite called trimethylamine N-oxide, or TMAO, could improve immunotherapy success in pancreatic cancer.

How Microbiotica Developed MB097, Live Bacterial Therapeutic that Could Boost Cancer Treatments

Ghaith Bakdash described how Microbiotica discovered a specific microbiome signature in patients responder to immune-oncology drugs such as anti-PD1 / PDL1 and developed a new bacterial consortium.

Bacteria in tumors may help cancer to metastasize

New research indicates that the tumor-resident microbiota can promote the formation of metastases as well as the survival of cancer cells during tumor progression.

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