Oncology

A specific strain of gut bacteria boosts cancer therapy in mice

The findings of a recent study suggest that the combination of anti-PD-1 immunotherapy with a lack of TREM2 generates a gut environment that promotes inflammation, which improves tumor rejection.

A high-fat diet promotes breast cancer by altering gut microbial metabolism

The findings of a recent study suggest that Desulfovibrio can drive cancer progression, paving the way for therapeutic approached that targeting the gut microbiota.

Vitamin D boosts cancer immunity by altering gut bacteria

The findings uncover a link between vitamin D, the immune system and gut bacteria, and they suggest that vitamin D levels could be important for cancer immunity and the efficacy…

Microbial signature linked to improved response to immunotherapy in older people

The findings of a recent study highlight the importance of considering age-related immune changes and gut microbiota composition for developing personalized immunotherapy approaches.

Microbial metabolites promote colon cancer by suppressing anti-tumor responses

A recent study demonstrated causation between microbial DCA metabolism and anti-tumor CD8+ T cell response in colorectal cancer.

How some gut microbes improve responses to cancer immunotherapy

The findings of a recent study suggest that L. johnsonii or its metabolite IPA could be used as a microbial-based approach to improve a person’s response to immunotherapy.

Mouth bacteria speed up pancreatic cancer growth in mice

Research done in mice shows that the mouth-dwelling bacterium Porphyromonas gingivalis can travel from the mouth to the pancreas, resulting in lesions that lead to cancer.

AI implementation for microbiome small molecule discovery & therapeutics

Antonio Gomes, Principal Scientist at Xbiome, talks about employing deep learning techniques to refine the prediction of natural product structures directly from gene sets.

Why microbiome therapies are the next frontier in oncology

Elran Haber, CEO at Biomica Ltd, discussed the emerging role of microbiome-based treatments in cancer care.

Immune signaling can influence tumors growth through microbial regulation

The findings of a recent study suggest that the crosstalk between gut microbes and the host’s immune system can influence the body’s defenses during cancer therapy.

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