Giorgia Guglielmi

Arresting microbiota development stunts immune system maturation in mice

A recent study shows that microbiota maturation during weaning contributes to normal immune development and protection from infection.

Gut microbes sway how people with lymphoma respond to immunotherapy

The findings of a recent study identified microbiota signatures that may allow clinicians to predict the outcomes of CAR-T immunotherapy.

A mother’s diet can change the infant microbiota, prevent respiratory infection

Diet-induced changes in the gut microbiota confer protection against respiratory infections by regulating the development of key components of the immune system.

How a common bacterium colonizes the gut

The findings of a recent study suggest that other gut microbes use liquid-liquid phase separation to colonize the gut, opening the way for new microbiota-based clinical applications.

Some gut microbes are associated with depression in premenopausal women

The findings of a recent study suggest that estradiol-degrading bacteria could be therapeutic targets for treating depression in some women.

Microbial metabolite may damage the DNA of gut stem cells

The findings of a recent study suggest that tilimycin-producing bacteria can cause genetic mutations in the colon and increase a person’s susceptibility to disease.

Immune cells may shuttle beneficial gut microbes to boost anticancer responses

The findings of a new study shed light on a general mechanism by which gut bacteria may influence anti-cancer immune responses.

Babies receive microbes from their mothers through multiple routes

The findings of a new study suggest that mothers transmit bacteria to their infants through multiple routes — a process that ensures that babies receive essential microbes.

A gut microbe can promote growth in mice

The findings of a new study suggest that providing at-risk populations with NOD2 ligands or probiotic bacteria that release high levels of NOD2-activating molecules may help to treat undernutrition.

Microbiota-derived metabolite may help combat pancreatic cancer

The findings of a new study suggest that the microbial metabolite 3-IAA could help to treat PDAC.

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