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IL-17 molecules from the gut can influence autoimmune diseases in the central nervous system by regulating the gut microbiota.
People with active multiple sclerosis have high levels of particular gut antibodies, called immunoglobulin A (IgA), in the central nervous systems.
According to a recent study, the gut microbiota could determine remittance or pro-inflammatory conditions in multiple sclerosis.
GDP-L-fucose synthase, a protein produced by bacteria often found in the gut of people with MS, triggers an autoimmune response from T-cells in MS patients.