cancer

Microbial metabolites promote colon cancer by suppressing anti-tumor responses

A recent study demonstrated causation between microbial DCA metabolism and anti-tumor CD8+ T cell response in colorectal cancer.

How some gut microbes improve responses to cancer immunotherapy

The findings of a recent study suggest that L. johnsonii or its metabolite IPA could be used as a microbial-based approach to improve a person’s response to immunotherapy.

Mouth bacteria speed up pancreatic cancer growth in mice

Research done in mice shows that the mouth-dwelling bacterium Porphyromonas gingivalis can travel from the mouth to the pancreas, resulting in lesions that lead to cancer.

AI implementation for microbiome small molecule discovery & therapeutics

Antonio Gomes, Principal Scientist at Xbiome, talks about employing deep learning techniques to refine the prediction of natural product structures directly from gene sets.

Gut metabolites may help to predict infection risk after liver transplant

The findings suggest that microbial metabolites can help to predict who is at increased risk of infection after liver transplant. The results may also help to inform microbiota-targeted therapies.

Why microbiome therapies are the next frontier in oncology

Elran Haber, CEO at Biomica Ltd, discussed the emerging role of microbiome-based treatments in cancer care.

Immune signaling can influence tumors growth through microbial regulation

The findings of a recent study suggest that the crosstalk between gut microbes and the host’s immune system can influence the body’s defenses during cancer therapy.

The PICASSO trial: painting a new future for melanoma patients

MaaT Pharma indicates completion of patient recruitment for the Phase 2a RCT Evaluating MaaT013 in combination with immune checkpoint inhibitors in metastatic melanoma.

Gut microbes may promote the recovery of liver function in cancer patients

The findings of a recent study suggest that modulating the gut microbiota in people with liver cancer can improve their health outcomes after surgery.

Unraveling disease-specific patterns: loss of microbial cross-feeding in the human gut

Focusing on restoring microbial cross-feeding interactions emerges as a promising mechanism-informed strategy to reconstruct a healthy gut ecosystem.

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