Scientific News

Pharmabiotics Conference 2026: three days in Brussels on microbiome biomarkers, one health, and a shifting regulatory landscape

Celine Druart, Executive Director at Pharmabiotic Research Institute, discusses the 10th Pharmabiotics Conference in Brussels, from microbiome biomarkers and One Health to key regulatory developments shaping live biotherapeutic products.

L. reuteri LMG P-27481: a new candidate to modulate barrier function and inflammation

Veronica Ojetti, gastroenterologist at San Carlo di Nancy Hospital (Italy), presents findings from a single-center pilot study assessing the effects of L. reuteri LMG P-27481 on the gut microbiota and…

Review finds no strong evidence for a causal link between gut microbes and autism

Future studies should have clearly defined hypotheses, adequate sample size, standardized protocols, and replication using multiple independent approaches.

Gut bacteria from mothers with IBD may increase disease risk in children

Changes in gut bacteria raise a child’s chances of developing IBD later in life, offering clues to why the conditions sometimes runs in families.

From microbiota to prognosis: the gut–liver axis moves into clinical care

Francesca Ponziani from Gemelli University Hospital (Italy) highlights how the gut microbiota can become a clinical tool for identifying and stratifying patients, clarifying pathogenic mechanisms, and opening up new therapeutic…

Some oral microbes may influence esophageal cancer risk

Certain harmful microbes in the mouth appear to promote cancer development, while others might help protect against it. 

Short-term steroid use may affect metabolism and immunity by reshaping gut bacteria 

Researchers set up a clinical trial to study how glucocorticoids affected the gut microbiota, metabolism, and immunity in healthy young men.

Microbiota–immunity cross-talk: two sides of the same coin in colorectal cancer and IBD

Federica Facciotti, from University of Milano Bicocca, focuses on how the gut microbiota interacts with immune activation, shaping both chronic inflammatory intestinal disorders and oncology, particularly colorectal cancer. 

Gut microbes protect the liver by digesting fatty liver-causing sugar, fish study shows

Gut bacteria help protect the liver by breaking down sorbitol, a sugar made from glucose in the gut.

Largest oral microbiota catalog reveals bacteria linked to oral and systemic health 

The researchers created a microbial catalog, which they called HROM (human reference oral microbiome), containing 72,641 high-quality genomes from 3,426 species.

Beyond bacteria: yeasts, trained immunity, and next-generation Saccharomyces probiotics

Duccio Cavalieri, professor at the University of Florence, shifts the spotlight from bacteria to the less-explored fungal and yeast communities of the microbiome, highlighting their emerging role in shaping host…

Microbial metabolites may help immune cells fight melanoma 

Diet and gut microbes can shape immune cell function and improve responses to anti-cancer therapy.

Some gut bacteria may reduce steroid hormone activity

A gut bacterium, Clostridium steroidoreducens, can chemically modify steroid hormones, including those used to treat IBD. 

Global probiotic supplements in 2024: A $9.4B market, China’s surge, Europe’s e-commerce paradox, and fragmented regulation

Microbiomepost conducted an exclusive interview with George Paraskevakos, Executive Director at International Probiotic Association in order to discuss the global market of biotic products in 2025.

Specific gut bacteria regulate intestinal motility by producing serotonin

L. mucosae and L. ruminis can produce serotonin in the gut, where it promotes nerve growth and regulates intestinal motility.

Distinct gut microbes and metabolites underlie differences in irritable bowel syndrome 

Researchers have found that certain gut bacteria and their metabolites differ between IBS subtypes.

Why probiotic health claims rarely succeed at EFSA: evidence standards, study populations, and the challenge of live microorganisms

Ger T. Rijkers, University College Roosevelt, Netherlands, discusses the regulatory frame about probiotics in Europe.

Fecal profiling of pancreatic cancer

Results of a recent study showed reduced microbial diversity and distinct microbial profile in the two groups of PC patients.

Probiotics and public health: small interventions, billion-Euro stakes

Mike Holland, who has spent decades valuing the health and economic impacts of policy choices for the European Commission, the European Environment Agency and the OECD, discusses the economic impact…

Gut bacteria may help predict lung cancer treatment success

Changes in gut bacteria, especially Akkermansia, could predict treatment success in people with lung cancer.

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