Several studies have shown that Lactiplantibacillus plantarum 6595 (Probi® Plantarum 6595) survives the passage through the GI tract, and attaches to the intestinal cells through a specific mannose-dependent binding mechanism. The bacteria can thereby exert its effects on the intestinal wall, and immune system. Lactiplantibacillus plantarum 6595 (Probi® Plantarum 6595) has also been shown to be present in the intestine up to 11 days after end of intake.