Dietary interventions may result in individualized or personalized responses in the gut microbiome and are often evaluated through DNA analysis alone. Using longitudinal sampling and simultaneous collection of stool DNA & RNA, combined with multiomic analysis, Diversigen explored the impact of intermittent fasting on the gut microbiome.
Emily Hollister (Diversigen) discussed during the Microbiome Connect: USA 2022 how by pairing metatranscriptomics with metagenomics to assess functional and taxonomic composition, the company demonstrate the rapidity of microbial gene expression changes potentially impacting host-microbiome interactions.
