Oncology

Gut microbes sway how people with lymphoma respond to immunotherapy

The findings of a recent study identified microbiota signatures that may allow clinicians to predict the outcomes of CAR-T immunotherapy.

Gut microbiome affects tumor regression of oncolytic adenovirus-treated melanoma

Microbiomepost discussed with Lorella Tripodi, University Federico II of Naples, about the research she is working with her colleagues.

How the sex hormone-gut microbiome axis influences tumor immunotherapy

Numerous evidences demonstrate the involvement of the sex hormone-gut microbiome axis in regulating the antitumor efficacy of ICIs.

Microbial metabolite may damage the DNA of gut stem cells

The findings of a recent study suggest that tilimycin-producing bacteria can cause genetic mutations in the colon and increase a person’s susceptibility to disease.

Immune cells may shuttle beneficial gut microbes to boost anticancer responses

The findings of a new study shed light on a general mechanism by which gut bacteria may influence anti-cancer immune responses.

Microbiota-derived metabolite may help combat pancreatic cancer

The findings of a new study suggest that the microbial metabolite 3-IAA could help to treat PDAC.

A Fusobacterium nucleatum vaccine to help protect against colorectal cancer?

Vaccines against F. nucleatum and other onco-microbes may help prevent diseases such as colorectal cancer.

Specific gut bacteria reduce ovarian cancer progression in mice

The findings of a recent study tie the gut microbiota to immune surveillance of ovarian cancer and may inform new treatment approaches.

The Future of Microbiome Modulation Immuno-Oncology

Fabio Grassi, Founder at MV BioTherapeutics SA, discussed how to understand the mechanisms of action for microbiome contributions to cancer therapeutic response in patients.

Fever after cancer therapy may be linked to specific gut microbes

The findings of a new research suggest that dietary and antibacterial strategies may help to prevent neutropenia-related fever after cancer therapy.

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