Gastroenterology

Microbial metabolites promote colon cancer by suppressing anti-tumor responses

A recent study demonstrated causation between microbial DCA metabolism and anti-tumor CD8+ T cell response in colorectal cancer.

Leaky gut is linked to accelerated biological aging in people with HIV

The findings of a recent study suggest that specific microbial signatures are associated with accelerated biological aging.

A gut microbial metabolite may promote blood clot formation

The findings of a recent study suggest that 2MBC exacerbates the susceptibility to thrombosis and may explain why people with COVID-19 are at increased thrombotic risk.

Gut bacteria may contribute to devastating eye diseases

The findings of a recent study suggest that inherited eye diseases are caused in part by gut bacteria that travel to the retina.

The microbiotas of men who have sex with men resemble those of non-Westernized people

The findings of a recent study suggest that specific sexual activities are associated with gut microbiota alterations in men who have sex with men.

Mouth bacteria speed up pancreatic cancer growth in mice

Research done in mice shows that the mouth-dwelling bacterium Porphyromonas gingivalis can travel from the mouth to the pancreas, resulting in lesions that lead to cancer.

Gut microbes may contribute to statin-associated high blood sugar levels

The findings show that statin-induced high blood sugar levels are associated with Clostridium bacteria and bile acids. The work also suggests that ursodiol may help reduce the adverse effects of…

The new frontier: polyclonal antibodies in microbiome editing

Satish Chandran, President and Chief Executive Officer at Prodigy Biotech, Inc., details the company's program aimed at treating alcoholic liver disease, spotlighting Enterococcus faecalis as the primary antagonist.

Diet switching quickly impacts the gut microbiota and immune system

Two weeks of dietary intervention are sufficient to influence host immunity, metabolism and gut microbiota composition.

Gut microbes may influence susceptibility to respiratory infections 

The results of a recent study reveal that the severity of respiratory infections depends at least in part on a complex interplay between the gut microbiota and the immune system.

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