Giorgia Guglielmi

Tumor-dwelling bacteria boost effectiveness of cancer therapy in mice

Three promising bacteria were linked to better treatment responses in melanoma patients.

Gut microbes help keep immune cells anchored in the intestine

Targeting the microbiota could be a new way to strengthen gut immunity and develop treatments for inflammatory bowel diseases such as Crohn’s disease.

Breast milk antibodies train newborn gut immunity, mice study shows

Antibodies in breast milk “teach” a newborn’s gut immune system to respond appropriately to microbes and maintain intestinal balance without causing unnecessary inflammation.

Gut bacteria studied at subspecies level reveal links to colorectal cancer

Profiling the human gut microbiota at the subspecies level, rather than at the species- or strain-level, provides more reproducible insights into how specific bacteria influence health and disease.

Gut bacteria cooperate to convert dietary compound into energy, boosting microbial health

Gut bacteria cooperate to convert the dietary antioxidant ergothioneine into a compound that supports energy production. 

Mice study reveals how drug-resistant bacteria take hold in the gut

The findings of a recent study reveal a key strategy used by A. baumannii to colonize the gut and persist in it, highlighting a potential target for preventing its spread…

Gut microbes may be linked to increased blood clotting and heart disease risk

Targeting specific gut bacteria and their metabolites could offer new ways to prevent or treat cardiovascular disease linked to diet and gut health.

Healthy immune cells may protect the gut barrier, prevent age-related inflammation 

Maintaining healthy T cells is key to preserving gut health and preventing chronic inflammation that drives aging-related diseases.

How gut microbiota and genetic factors may drive inflammatory bowel disease

By revealing that OTUD3 limits microbiota-driven STING activation, the findings of a new study offer insights into the disease mechanisms of ulcerative colitis and may pave the way to new…

Engineered gut bacteria may help deliver therapies

Engineered bacteria can be used in gut therapies, but maintaining control over their colonization and genetic stability remains challenging.

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