cancer

How gut microbes boost immune responses to cancer immunotherapy

The findings show that bacterial metabolites can sensitize cancer cells to treatment with immunotherapy by boosting the expression of HLA class I molecules.

How do antibiotics influence the microbiota’s impacts on immunotherapy?

Understanding how antibiotics influence the microbiota’s impacts on immunotherapy may inform strategies to identify cancer patients that are more likely to respond to cancer treatment.

MaaT Pharma Announces European Medicines Agency Granted MaaT033 Orphan Drug Designation Aiming to Improve Overall Survival in Patients Undergoing Hematopoietic Stem Cell transplantation

MaaT033 (capsule), which is being developed as an adjunctive and maintenance therapy to improve overall survival in allo-HSCT, has received orphan drug designation (ODD) status from the European Medicines Agency…

Microbiota transplant may alleviate intestinal side effects of cancer immunotherapy

The findings of a recent study suggest that FMT is an effective strategy to mitigate the intestinal side effects of cancer immunotherapy.

Engineer single strain LBPs for robust tumor microenvironment disruption

Pedro Correa de Sampaio, Chief Executive Officer at Neobe Therapeutics, talks about the challenges to remove immunosuppressive constraints that prevent the infiltration of immune cells in a subset of cancers.

Antibiotics may alter gut microbes in ways that hinder cancer immunotherapy

The findings of a recent study suggest that targeting the interactions between MAdCAM-1 and specific receptors on the surface of immune cells may help to improve immunotherapy outcomes.

Preclinical data for MaaT03X, designed to improve response rate to immune checkpoint inhibitors in a solid tumor indication

Nathalie Corvaïa, Chief Scientific Officer at MaaT Pharma, gives an overview of preclinical and clinical results for MaaT013 and MaaT033.

Mainz Biomed Partners with Microba Life Sciences for the Development of PancAlert

This partnership aims to leverage Microba's advanced technology platform for measuring the human gut microbiome to discover novel biomarkers for pancreatic cancer detection. 

Gut microbes sway how people with lymphoma respond to immunotherapy

The findings of a recent study identified microbiota signatures that may allow clinicians to predict the outcomes of CAR-T immunotherapy.

Gut microbiome affects tumor regression of oncolytic adenovirus-treated melanoma

Microbiomepost discussed with Lorella Tripodi, University Federico II of Naples, about the research she is working with her colleagues.

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