MetSyn is a probiotic complex by SynBalance, specifically formulated to support individuals with metabolic syndrome. A randomized, double-blind, placebo-controlled clinical trial demonstrated its ability to improve key metabolic and inflammatory markers, while also enhancing lipid and cholesterol profiles, underscoring the added value of probiotic supplementation alongside lifestyle modifications. Additionally, recent in vitro studies have revealed its efficacy against the harmful stimuli associated with dysbiosis and increased intestinal permeability, with a particular focus on their impact on vascular health, implying a possible positive impact on cardiovascular conditions, including hypertension and endothelial dysfunction.