KeepCalm, a probiotic complex by SynBalance, is designed to support stress relief and emotional well-being. Its efficacy has been demonstrated in three clinical trials across different high-stress conditions: on students during exams, on workers during the Covid-19 pandemic and on postpartum women. Results showed its ability to improve mood and sleep quality, while supporting mental wellness and improving attention.
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SynbÆctive® KeepCalm
Discover characteristics, functionalities and scientific support of SynbÆctive® KeepCalm.
Thearapeutical Area(s): Gut brain Axis
Age/Gender: Adults
Dosage Form: sachets, capsule, sticks, tablets, triphase vials, bulk
CFU/Dose: 4 billion(s)
Scientific reference(s)
Nobile V, Giardina S, Puoci F: The Effect of a Probiotic Complex on the Gut-Brain Axis: A Translational Study. Neuropsychobiology 2021. doi: 10.1159/000518385
Nobile, Vincenzo, and Francesco Puoci. “”Effect of a Multi-Strain Probiotic Supplementation to Manage Stress during the COVID-19 Pandemic: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Clinical Trial.”” Neuropsychobiology (2023): 1-11.
Vicariotto, Franco, et al. “Beneficial Effects of Limosilactobacillus reuteri PBS072 and Bifidobacterium breve BB077 on Mood Imbalance, Self-Confidence, and Breastfeeding in Women during the First Trimester Postpartum.” Nutrients 15.16 (2023): 3513.
The KeepCalm strains have been selected through in-vitro screening based on neurotransmitters enhancement as serotonin and GABA, and modulation of epigenetic enzymes.